LjaFGD


Enzyme information


Sphingolipid signaling pathway


Protein KO Enzyme Annotation
GWHPAAZE017652 K00654 SPT serine palmitoyltransferase [EC:2.3.1.50]
GWHPAAZE024468 K00654 SPT serine palmitoyltransferase [EC:2.3.1.50]
GWHPAAZE030803 K00654 SPT serine palmitoyltransferase [EC:2.3.1.50]
GWHPAAZE018578 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE023424 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE023445 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE029753 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE033120 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE006141 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE006142 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE006153 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE012261 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE012262 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE013864 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE014980 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE016655 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE017511 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE017512 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE019539 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE022202 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE024452 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE025551 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE025552 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE028864 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE029370 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE029371 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE029372 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE029646 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE030920 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE031033 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE031362 K01115 PLD1_2 phospholipase D1/2 [EC:3.1.4.4]
GWHPAAZE013740 K01634 SGPL1, DPL1 sphinganine-1-phosphate aldolase [EC:4.1.2.27]
GWHPAAZE009720 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE013389 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE022667 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE022675 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE004970 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE008239 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE017355 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE017949 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE023859 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE031029 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE025738 K04368 MAP2K1, MEK1 mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
GWHPAAZE009179 K04371 ERK, MAPK1_3 mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
GWHPAAZE001613 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE001623 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE008353 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE008368 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE013576 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE013577 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE022877 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE025172 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE031648 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE031649 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE004630 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE007582 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE013890 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE014963 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE016637 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE018333 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE025680 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE026842 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE030209 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE030569 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE031237 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE006620 K04712 DEGS sphingolipid 4-desaturase/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]
GWHPAAZE004730 K04718 SPHK sphingosine kinase [EC:2.7.1.91]
GWHPAAZE000393 K05665 ABCC1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
GWHPAAZE009640 K05665 ABCC1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
GWHPAAZE025130 K05665 ABCC1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
GWHPAAZE031211 K05665 ABCC1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3]
GWHPAAZE005096 K06276 PDPK1 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
GWHPAAZE012904 K06276 PDPK1 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
GWHPAAZE005215 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE009674 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE012187 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE002401 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE005684 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE013228 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE013229 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE018312 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE023026 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE025408 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE025609 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE026983 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE028628 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE033340 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE009310 K12349 ASAH2 neutral ceramidase [EC:3.5.1.23]
GWHPAAZE013047 K12349 ASAH2 neutral ceramidase [EC:3.5.1.23]
GWHPAAZE013048 K12349 ASAH2 neutral ceramidase [EC:3.5.1.23]
GWHPAAZE013847 K12349 ASAH2 neutral ceramidase [EC:3.5.1.23]
GWHPAAZE013428 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
GWHPAAZE018552 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
GWHPAAZE022716 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
GWHPAAZE022717 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
GWHPAAZE029968 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]
GWHPAAZE030457 K23727 CERS5_6, LASS5_6 sphingoid base N-palmitoyltransferase [EC:2.3.1.291]


Pathway information

map04071