LjaFGD


Enzyme information


PI3K-Akt signaling pathway


Protein KO Enzyme Annotation
GWHPAAZE018578 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE023424 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE023445 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE029753 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE033120 K01110 PTEN phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
GWHPAAZE012461 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE015037 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE022468 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE025913 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE025914 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE028463 K02206 CDK2 cyclin-dependent kinase 2 [EC:2.7.11.22]
GWHPAAZE007848 K02991 RP-S6e, RPS6 small subunit ribosomal protein S6e
GWHPAAZE017034 K02991 RP-S6e, RPS6 small subunit ribosomal protein S6e
GWHPAAZE029924 K02991 RP-S6e, RPS6 small subunit ribosomal protein S6e
GWHPAAZE004230 K03259 EIF4E translation initiation factor 4E
GWHPAAZE006750 K03259 EIF4E translation initiation factor 4E
GWHPAAZE021852 K03259 EIF4E translation initiation factor 4E
GWHPAAZE009720 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE013389 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE022667 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE022675 K03456 PPP2R1 serine/threonine-protein phosphatase 2A regulatory subunit A
GWHPAAZE002977 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE003592 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE004947 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE006435 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE009128 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE026287 K04079 HSP90A, htpG molecular chaperone HtpG
GWHPAAZE004970 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE008239 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE017355 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE017949 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE023859 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE031029 K04354 PPP2R2 serine/threonine-protein phosphatase 2A regulatory subunit B
GWHPAAZE025738 K04368 MAP2K1, MEK1 mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]
GWHPAAZE009179 K04371 ERK, MAPK1_3 mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
GWHPAAZE001613 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE001623 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE008353 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE008368 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE013576 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE013577 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE022877 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE025172 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE031648 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE031649 K04382 PPP2C serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
GWHPAAZE004630 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE007582 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE013890 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE014963 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE016637 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE018333 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE025680 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE026842 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE030209 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE030569 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE031237 K04392 RAC1 Ras-related C3 botulinum toxin substrate 1
GWHPAAZE030050 K04536 GNB1 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
GWHPAAZE013211 K04659 THBS2S thrombospondin 2/3/4/5
GWHPAAZE005309 K04688 RPS6KB ribosomal protein S6 kinase beta [EC:2.7.11.1]
GWHPAAZE017880 K04688 RPS6KB ribosomal protein S6 kinase beta [EC:2.7.11.1]
GWHPAAZE026490 K04688 RPS6KB ribosomal protein S6 kinase beta [EC:2.7.11.1]
GWHPAAZE001305 K05635 LAMC1 laminin, gamma 1
GWHPAAZE005096 K06276 PDPK1 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
GWHPAAZE012904 K06276 PDPK1 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
GWHPAAZE010792 K06626 CCNE G1/S-specific cyclin-E1
GWHPAAZE001885 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE001888 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE002062 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE002633 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE003116 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE003117 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE006682 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE007403 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE007828 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE013475 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE014269 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE014309 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE014330 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE014818 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE015188 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE016280 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE016321 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE017036 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE018739 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE022768 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE027133 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE029923 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE032749 K06630 YWHAE 14-3-3 protein epsilon
GWHPAAZE000602 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE003361 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE003976 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE004567 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE005328 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE006699 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE006701 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE009424 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE012354 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE014400 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE017794 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE022320 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE033129 K07198 PRKAA, AMPK 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
GWHPAAZE018652 K07203 MTOR, FRAP, TOR serine/threonine-protein kinase mTOR [EC:2.7.11.1]
GWHPAAZE005339 K07204 RAPTOR regulatory associated protein of mTOR
GWHPAAZE005340 K07204 RAPTOR regulatory associated protein of mTOR
GWHPAAZE012967 K07204 RAPTOR regulatory associated protein of mTOR
GWHPAAZE004467 K08266 MLST8, GBL target of rapamycin complex subunit LST8
GWHPAAZE026254 K08266 MLST8, GBL target of rapamycin complex subunit LST8
GWHPAAZE002471 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE004721 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE013442 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE013443 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE013897 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE016630 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE022725 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE027022 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE031522 K09487 HSP90B, TRA1 heat shock protein 90kDa beta
GWHPAAZE005215 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE009674 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE012187 K11583 PPP2R3 serine/threonine-protein phosphatase 2A regulatory subunit B''
GWHPAAZE002401 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE005684 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE013228 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE013229 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE018312 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE023026 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE025408 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE025609 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE026983 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE028628 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'
GWHPAAZE033340 K11584 PPP2R5 serine/threonine-protein phosphatase 2A regulatory subunit B'


Pathway information

map04151